Tuesday, July 12, 2022

Rainbow-striped Zebra

The classic metaphor of the zebra in medicine harkens back to either Maryland in the 1940's or Arkansas in the 1960's when medical students were advised: "When you hear hoofbeats in the night, look for horses - not zebras." (1) With this simple instruction, the concepts of clinical acumen and outlier awareness have permeated our healthcare culture so we are ironically looking for and sometimes celebrating the zebras we find.

Although common things happen commonly, we are on a safari for a good pick-up, as they are called, when we proactively discover an uncommon disorder that a more casual observer may have overlooked. Those rarities sometimes occur in a Pareto (2) distribution to the extreme or push the bell curve (3) and our diagnostic curiosity to the narrow and more remote heads or tails of a Gaussian function.

Even if there is the chance of a problem being that one out of a million occurrence, we need to construct what is called a differential diagnosis (or differential, for short), a laundry list of the entire constellation of possibilities, sometimes even organized in the order of the complex and interrelated systems of the human body. In turn, a Bayesian approach guides a thorough history taking, a targeted physical examination, and appropriate testing to gravitate toward a solution so we find the solid ground of evidence and stick the landing with more sure footing.

Teenage well-child checks can be the most challenging visits on our schedules in primary care. These creatures' social awkwardness, changing parent dynamics, and reticence to the required counseling topics of “sex, drugs and rock ‘n roll” are daunting, especially since the entire task is usually inserted into a meager 15 to 20-minute timeslot. A positive review of systems for mental health, attention issues or school performance will wreck your timeliness metric for the rest of the morning or afternoon.

One of my most memorable visits in private practice was with a high school sophomore who had the typical disheveled look on the exam table with tossed hair, torn jeans, and mismatched clothes. Her low level of engagement and lack of eye contact were predictable components of the standard presentation. Once the birds and the bees and requisite substance use topics were covered, rock ‘n roll was the prompt for me to engage a bit more with my patients and ask about broader social-related items: favorite music, interesting hobbies, creative endeavors, or athletic outlets such as school clubs, community groups, church activities, the arts or sports. Everything is fair game to make a connection.

She sheepishly muttered under her floppy hair, “I paint.”

“Really, that’s awesome!” I said. “What medium do you use? Oils? Watercolors? Acrylics?”

“All of them. I just like to paint and draw.” was the answer in a non-descript adolescent way.

I had encountered some amazing stories over the years by showing curiosity in these growing human beings, expressing interest in them as a person and their unique attributes. Kids from the farms told me about their most recent rabbit or chicken they had shown at the fair. Athletes told me about their most recent games or travels. Anime fans related what they had discovered at the most recent convention they had attended. Budding young artists or their parents often snapped pictures on their phones so I could view samples of their work which is what I was hoping to find in this case.

“Well, what do you typically paint as your subjects?” was my volley back to her.

Once again, she was evasive. “Different things.” was her reply followed by a slight pause. Then she looked up at me with a focus and zeal I had not seen until that point, “I painted a zebra last week.”

I now had my in. “That's awesome!" I exclaimed. "Zebras are famous in medicine!” I gave a summary of the fabled history and how applicable these animals are to my role as a family physician and the charge to herd the common horses while scanning for the unusual zebras.

Almost apologetically, she then admitted to me “It’s a rainbow-striped zebra.” as if I would be disappointed in her more abstract interpretation of the black and white version. My response was even more excitable since that metaphor is what my wife had always talked about as the rare findings in her own clinical experiences as an occupational therapist: a rainbow-striped zebra, the combination of a naturally occurring animal with fantastical magic, unanticipated wonder, and significant promise from its outward expression of graceful form and unique content. She had witnessed patients present to her hospital rehabilitation unit under the strangest and most dire of circumstances from strokes, multi-trauma car crashes, surgical complications, spinal cord injuries, or traumatic brain injuries. Nonetheless, these patients conjured up unseen powers to walk again, talk again, or express their unbound love in other explicit ways when no one had believed such activities would ever happen again.

Her mother then piped up with pride: “She has a whole portfolio if you want to see it.”

“Of course!” I said. “Come by any time so I can see what you have painted.” was my simple but earnest ask. We ended the rest of the visit with the standard review of the shot record and additional health and safety counseling related to diet, exercise, seat belts, helmets, and firearms. I said goodbye and they checked out of the clinic.

A few days later, I was seeing a full schedule of patients and my reception staff sent an instant message to me over our computer system. “There’s a family here at the front desk who wants to show you some art.”

“Send them to the second waiting area please” was my response.

After the patient on hand was checked out, I went to find the girl, her mother, and the little brother who was bouncing on the nearby cushy chair. Using the side table as a display stand, they proceeded to show me each of her paintings, drawings, or sketches with great care but at a deliberate pace.

They stopped at the zebra. She was gorgeous. Vibrant streaks and esoteric dots emanated from each of the stripes with radiant leaves and flowers showering this majestic creature in a variegated stream of color and energy. A dark red rose was perched behind her right ear as a stroke of beauty and grace.

“It’s beautiful!” was all I could say. This artist had found and captured the elusive rainbow-striped zebra in perfect form and detail. I was in awe.

“You can have it.” she said.

I denied such a privilege. “I can’t just take this.” I replied. It was too much for even me who had received many patient gifts in my rural practice over the years: fresh eggs, fruit, smoked fish, books, a knit scarf, a crocheted pillow, crazy socks and even a baseball signed by a patient’s grandfather, a former Detroit Tiger now confined to a wheelchair after a stroke. I was still mesmerized by the sight in front of me.

“Paint and brushes aren’t cheap.” was her mother’s response. I awoke from my gaze and caught her signal. Purely out of dumb luck, I had a substantial amount of cash in my wallet. I completed a more reasonable exchange of goods for money to subsidize the healthy habit of art for my patient and gain a newfound prize for our practice.

Several weeks later, I received the phone call from the local frame shop for pick-up where I had a simple black mat and border placed around my new wall decoration. I hung it in the hallway between my two designated patient rooms for the next three years before management did a clinic renovation with new carpet and paint on the walls. At the time, I was taking up a new position at a teaching program in family medicine at a different location, so the timing was right for me to move out anyway. I brought the painting home thinking this may be another piece of swag that would not make the cut for my next office and be set to the side with other relics of my career.

Around this same transition time, I was preparing for other milestones, turning 50 on April 22nd and celebrating a military retirement ceremony on May 7th. Following my own well-adult health check, I learned the worsening vision, unintended weight loss, and frequent urination over the prior three months had a cause that would be one more milestone of sorts. On May 17th, 2022, I was formally diagnosed with Type 1 diabetes. Although I had run one of my routine 5K routes around the neighborhood a few days prior and our family ate relatively healthy, my immune system had been triggered by a mechanism we will never know and was slowly attacking the insulin-producing islet cells in my pancreas. Close friends, coworkers, and relatives were surprised to hear a relatively healthy guy, out of the blue, could be diagnosed so dramatically with a lifelong chronic disease. Due to a family history of prostate cancer and the urinary symptoms, we had been more concerned with the possibility of cancer so the odd diagnosis of diabetes at my age was, in fact, a welcome finding from much worse diagnoses that were sitting on the differential. The negative CT scan to rule out a malignancy in my belly was a welcome datapoint when that result showed up in the patient portal within 18 hours of leaving the radiology suite.

As our family was setting up the home office for my new administrative job with the health system, we considered the various options we had as a background for teleconferences or remote meetings. There was no question about what came out of the collection of artwork, photographs, and certificates in the nearby closet. My wife insisted the rainbow-striped zebra be the centerpiece to the newly painted wall opposite my colorful military shadowbox of patches and badges along with other memorabilia hanging nearby. They all formed complementary colors and images with symbolic messages of hope, peace, and joy from expected and unexpected sources.

I am a rainbow-striped zebra. So are you. Start painting.

1 https://quoteinvestigator.com/2017/11/26/zebras/

2 https://en.wikipedia.org/wiki/Pareto_distribution

3 https://en.wikipedia.org/wiki/Normal_distribution